Article
Prevalence of class I-III BRAF mutations among 114,662 cancer patients in a large genomic database.
Experimental biology and medicine (Maywood, N.J.) - 1 Jan 2021
Owsley Jeff, Stein Matthew K, Porter Jason, In Gino K, Salem Mohamed, O'Day Steven, Elliott Andrew, Poorman Kelsey, Gibney Geoffrey, VanderWalde Ari
Abstract excerpt
IMPACT STATEMENT: These data represent the largest aggregation of BRAF mutations within a single clinical database to our knowledge. The relative proportions of both BRAF V600 mutations and non-V600 mutations are informative in all cancers and by malignancy, and can serve as a definitive gold-standard for BRAF mutation cancer incidence by malignancy. The rate of BRAF mutation in human cancer in a real-world large...
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