Article
Genetic analysis of the RELN gene: Gender specific association with Alzheimer's disease.
Psychiatry research - 15 Dec 2015
Fehér Ágnes, Juhász Anna, Pákáski Magdolna, Kálmán János, Janka Zoltán
Abstract excerpt
Association between genetic variants of the reelin (RELN) gene and the risk for developing Alzheimer's disease (AD) was examined in a sample of 432 patients and 308 controls. Single marker and haplotype analyses revealed that the strongly linked rs528528 and rs607755 polymorphisms are associated with AD risk in a gender specific manner. Among men, but not in women the rs528528 T/T and rs607755 A/A genotypes were...
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