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Article

The RELN locus in Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jul 2008

Seripa Davide, Matera Maria Giovanna, Franceschi Marilisa, Daniele Antonio, Bizzarro Alessandra, Rinaldi Monica, Panza Francesco, Fazio Vito Michele, Gravina Carolina, D'Onofrio Grazia, Solfrizzi Vincenzo, Masullo Carlo, Pilotto Alberto

Abstract excerpt

Reelin, a serine protease encoded by the RELN gene, is part of the apolipoprotein E (apoE) biochemical pathway that is involved in the pathogenesis of Alzheimer's disease (AD). Sex-related differences in the epidemiology, pathology and clinical characteristics of AD have been reported. To explore the potential contribution of RELN gene variants in the pathogenesis of AD, we investigated three polymorphisms...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules, Neuronal

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Source

Identifiers

PMID: 18599960
DOI: 10.3233/jad-2008-14308

Genes

RELN
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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