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HLA-DQ Mismatches Lead to More Unacceptable Antigens, Greater Sensitization, and Increased Disparities in Repeat Transplant Candidates

31 Aug 2022

Abstract excerpt

BACKGROUND: In single-center studies, HLA-DQ mismatches stimulate the most pathogenic donor-specific antibodies. However, because of limitations of transplant registries, this cannot be directly confirmed with registry-based analyses. METHODS: We evaluated patients in the Scientific Registry of Transplant Recipients who were relisted after renal graft failure with new, unacceptable antigens corresponding to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36450598
DOI: 10.1681/asn.2022030296

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