Article
Association of Bw4/Bw6 mismatch across class I HLA loci with renal graft outcomes in first time transplants.
Human immunology - 1 Oct 2021
Tang Mei San, Wang Mei, Chang Su-Hsin, Alhamad Tarek, Liu Chang
Abstract excerpt
Bw4 and Bw6 are strongly immunogenic epitopes routinely assigned based on HLA-B typing results per Organ Procurement and Transplantation Network (OPTN) policies. These public epitopes and their variants are shared by some cross-reactive HLA-A and -C antigens. Although epitope mismatch has been associated with poor transplant outcomes, previous studies did not find such associations for Bw4/6 mismatch as defined...
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