Article
Association of the FCN2 Gene Single Nucleotide Polymorphisms with Susceptibility to Pulmonary Tuberculosis.
PloS one - 1 Jan 2015
Xu Dan-Dan, Wang Chong, Jiang Feng, Wei Li-Liang, Shi Li-Ying, Yu Xiao-Mei, Liu Chang-Ming, Liu Xue-Hong, Feng Xian-Min, Ping Ze-Peng, Jiang Ting-Ting, Chen Zhong-Liang, Li Zhong-Jie, Li Ji-Cheng
Abstract excerpt
Ficolin-2 (FCN2) is an innate immune pattern recognition molecule that can activate the complement pathway, opsonophagocytosis, and elimination of the pathogens. The present study aimed to investigate the association of the FCN2 gene single nucleotide polymorphisms (SNPs) with susceptibility to pulmonary tuberculosis (TB). A total of seven SNPs in exon 8 (+6359 C>T and +6424 G>T) and in the promoter region (-986...
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