Article
A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations.
BMC infectious diseases - 14 Apr 2012
Zhao Mengyuan, Jiang Feng, Zhang Wanjiang, Li Fujian, Wei Liliang, Liu Jiyan, Xue Yun, Deng Xiling, Wu Fang, Zhang Le, Zhang Xing, Zhang Yuxiang, Fan Dapeng, Sun Xiaojun, Jiang Tingting, Li Ji-Cheng
Abstract excerpt
BACKGROUND: The present study aimed to investigate the genetic polymorphisms in exon 4 of the NOD2 gene in tuberculosis patients and healthy controls, in order to clarify whether polymorphisms in the NOD2 gene is associated with tuberculosis. METHODS: A case-control study was performed on the Chinese Han, Uygur and Kazak populations. Exon 4 of the NOD2 gene was sequenced in 425 TB patients and 380 healthy...
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