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Article

Acenocoumarol Pharmacogenetic Dosing Algorithms and Their Application in Two Bulgarian Patients with Low Anticoagulant Requirements.

Biochemical genetics - 1 Dec 2015

Dimitrova-Karamfilova Antoaneta, Tzveova Reni, Chilingirova Nezabravka, Goranova Teodora, Nachev Gencho, Mitev Vanio, Kaneva Radka

Abstract excerpt

BACKGROUND: The anticoagulant therapy with acenocoumarol is generally associated with a high risk of bleeding and thromboembolic events. PURPOSE: We applied eight already existing acenocoumarol dosing algorithms to Bulgarian patients with low acenocoumarol dose requirements and investigated which of these algorithms would predict most precisely the dose anticoagulant. MATERIALS AND METHODS: Two patients with...

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Source

Identifiers

PMID: 26377995
DOI: 10.1007/s10528-015-9695-8

Genes

VKORC1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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