Article
Cre-Mediated Recombination in Tas2r131 Cells-A Unique Way to Explore Bitter Taste Receptor Function Inside and Outside of the Taste System.
Chemical senses - 1 Nov 2015
Voigt Anja, Hübner Sandra, Döring Linda, Perlach Nathalie, Hermans-Borgmeyer Irm, Boehm Ulrich, Meyerhof Wolfgang
Abstract excerpt
The type 2 taste receptors (Tas2rs) comprise a large family of G protein-coupled receptors that recognize compounds bitter to humans and aversive to vertebrates. Tas2rs are expressed in both gustatory and nongustatory tissues, however, identification and functional analyses of T2R-expressing cell...
Topics
- Animals
- Genes, Reporter
- Genetic Vectors
- Genotype
- In Situ Hybridization, Fluorescence
- Integrases
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Microscopy, Fluorescence
- Receptors, G-Protein-Coupled
- Recombination, Genetic
- Taste Buds
- Transducin
- Taste Receptors, Type 2