Article
A Binary Genetic Approach to Characterize TRPM5 Cells in Mice.
Chemical senses - 1 Jul 2015
Kusumakshi Soumya, Voigt Anja, Hübner Sandra, Hermans-Borgmeyer Irm, Ortalli Ana, Pyrski Martina, Dörr Janka, Zufall Frank, Flockerzi Veit, Meyerhof Wolfgang, Montmayeur Jean-Pierre, Boehm Ulrich
Abstract excerpt
Transient receptor potential channel subfamily M member 5 (TRPM5) is an important downstream signaling component in a subset of taste receptor cells making it a potential target for taste modulation. Interestingly, TRPM5 has been detected in extra-oral tissues; however, the function of extra-gustatory TRPM5-expressing cells is less well understood. To facilitate visualization and manipulation of TRPM5-expressing...
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