Article
Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25.
BMC biology - 30 Mar 2006
Clapp Tod R, Medler Kathryn F, Damak Sami, Margolskee Robert F, Kinnamon Sue C
Abstract excerpt
BACKGROUND: Taste receptor cells are responsible for transducing chemical stimuli from the environment and relaying information to the nervous system. Bitter, sweet and umami stimuli utilize G-protein coupled receptors which activate the phospholipase C (PLC) signaling pathway in Type II taste cells. However, it is not known how these cells communicate with the nervous system. Previous studies have shown that the...
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