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Article

Potentially functional polymorphisms in PAK1 are associated with risk of lung cancer in a Chinese population.

Cancer medicine - 1 Nov 2015

Zheng Mingfeng, Liu Jia, Zhu Meng, Yin Rong, Dai Juncheng, Sun Jie, Shen Wei, Ji Yong, Jin Guangfu, Ma Hongxia, Dong Jing, Xu Lin, Hu Zhibin, Shen Hongbing

Abstract excerpt

P21-activated kinase 1(PAK1) plays an important role in the regulation of cell morphogenesis, motility, mitosis, and angiogenesis and has been implicated with tumorigenesis and tumor progression. We hypothesized that functional polymorphisms in PAK1 gene may modify the risk of lung cancer. We screened four potentially functional polymorphisms (rs2154754, rs3015993, rs7109645, and rs2844337) in PAK1 gene and...

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Identifiers

PMID: 26377044
DOI: 10.1002/cam4.524
PMCID: PMC4674004

Genes

PAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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