PARP-1 rs3219073 polymorphism may contribute to susceptibility to lung cancer.

doi:10.1089/gtmb.2014.0106

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PARP-1 rs3219073 polymorphism may contribute to susceptibility to lung cancer.

Genetic testing and molecular biomarkers - 1 Nov 2014

Wang He-Tong, Gao Ya, Zhao Yu-Xia, Yu Hong, Wang Tian-Lu, Bai Lu, Chen Yan-Zhi, Zhang Hai-Bo, Zhou Bao-Sen, Qu Yan-Li, Liu Dan, Chen Ying

Abstract excerpt

OBJECTIVE: To investigate the relationship between the PARP-1 rs3219073 C>G polymorphism and susceptibility to lung cancer in Chinese people. METHODS: In accordance with the case-control study principle, 645 of the patients had histologically recognized primary lung cancer, among them 240 had squamous carcinoma, 217 had adenocarcinoma, and 188 had small-cell lung cancer. The control group consisted of 643 healthy...

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PMID: 25225750
DOI: 10.1089/gtmb.2014.0106

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