Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sipa1 promoter polymorphism predicts risk and metastasis of lung cancer in Chinese.

Molecular carcinogenesis - 1 Nov 2013

Xie Chenli, Yang Lei, Yang Xiaorong, Yang Rongrong, Li Yinyan, Qiu Fuman, Chen Mei, Fang Wenxiang, Bin Xiaonong, Deng Jieqiong, Huang Dongsheng, Liu Bin, Zhou Yifeng, Lu Jiachun

Abstract excerpt

Signal-induced proliferation associated gene 1 (Sipa1) is a signal transducer to activate the Ras-related proteins and modulate cell progression, differentiation, adhesion and cancer metastasis. In this study, we tested the hypothesis that single nucleotide polymorphisms (SNPs) in Sipa1 are associated with lung cancer risk and metastasis. Three common SNPs (rs931127A > G, rs2448490G > A, and rs3741379G > T) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Large Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to GTPase-Activating Proteins

Share to Neoplasm Staging

Share to Nuclear Proteins

Share to Small Cell Lung Carcinoma

Share to Survival Rate

Source

Identifiers

PMID: 23661532
DOI: 10.1002/mc.22039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sipa1 promoter polymorphism predicts risk and metastasis of lung cancer in Chinese.PMID 23661532Read ↗

The SIPA1 -313A>G polymorphism is associated with prognosis in inoperable non-small cell lung cancer.Semantic proximity Read ↗

The association of SIPA1 gene polymorphisms with breast cancer risk: evidence from published studies.Semantic proximity Read ↗

Association of SIPA1 545 C > T polymorphism with survival in Chinese women with metastatic breast cancer.Semantic proximity Read ↗

Putative association of the single nucleotide polymorphisms in RASSF1A promoter with Korean lung cancer.Semantic proximity Read ↗

Polymorphisms of the SIPA1 gene and sporadic breast cancer susceptibility.Semantic proximity Read ↗

Potentially functional polymorphisms in PAK1 are associated with risk of lung cancer in a Chinese population.Semantic proximity Read ↗

Genetic variation in SIPA1 in relation to breast cancer risk and survival after breast cancer diagnosis.Semantic proximity Read ↗

The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations.Semantic proximity Read ↗

Cancer stem cell marker Musashi-1 rs2522137 genotype is associated with an increased risk of lung cancer.Semantic proximity Read ↗

Association of RASSF1A promoter methylation with lung cancer risk: a meta-analysis.Semantic proximity Read ↗

Functional PIN1 promoter polymorphisms associated with risk of nasopharyngeal carcinoma in Southern Chinese populations.Semantic proximity Read ↗

Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.