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Article

A novel locus in the oxidative stress-related gene ALOX12 moderates the association between PTSD and thickness of the prefrontal cortex.

Psychoneuroendocrinology - 1 Dec 2015

Miller Mark W, Wolf Erika J, Sadeh Naomi, Logue Mark, Spielberg Jeffrey M, Hayes Jasmeet P, Sperbeck Emily, Schichman Steven A, Stone Angie, Carter Weleetka C, Humphries Donald E, Milberg William, McGlinchey Regina

Abstract excerpt

Oxidative stress has been implicated in many common age-related diseases and is hypothesized to play a role in posttraumatic stress disorder (PTSD)-related neurodegeneration (Miller and Sadeh, 2014). This study examined the influence of the oxidative stress-related genes ALOX 12 and ALOX 15 on the association between PTSD and cortical thickness. Factor analyses were used to identify and compare alternative models...

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Identifiers

PMID: 26372769
DOI: 10.1016/j.psyneuen.2015.09.003
PMCID: PMC4637246

Genes

ALOX12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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