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Article

SKA2 methylation is associated with decreased prefrontal cortical thickness and greater PTSD severity among trauma-exposed veterans.

Molecular psychiatry - 1 Mar 2016

Sadeh N, Spielberg J M, Logue M W, Wolf E J, Smith A K, Lusk J, Hayes J P, Sperbeck E, Milberg W P, McGlinchey R E, Salat D H, Carter W C, Stone A, Schichman S A, Humphries D E, Miller M W

Abstract excerpt

Methylation of the SKA2 (spindle and kinetochore-associated complex subunit 2) gene has recently been identified as a promising biomarker of suicide risk. Based on this finding, we examined associations between SKA2 methylation, cortical thickness and psychiatric phenotypes linked to suicide in trauma-exposed veterans. About 200 trauma-exposed white non-Hispanic veterans of the recent conflicts in Iraq and...

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Source

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Identifiers

PMID: 26324104
DOI: 10.1038/mp.2015.134
PMCID: PMC4760869

Genes

SKA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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