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Article

Does deficiency of von Willebrand factor protect against cardiovascular disease? Analysis of a national discharge register.

Journal of thrombosis and haemostasis : JTH - 1 Nov 2015

Seaman C D, Yabes J, Comer D M, Ragni M V

Abstract excerpt

INTRODUCTION: von Willebrand factor (VWF) plays a critical role in platelet adhesion and aggregation after vascular injury and at sites of high shear rate. Elevated VWF levels are associated with an increased risk of ischemic cardiovascular events; however, it is unclear whether VWF deficiency is protective against atherosclerosis. We aimed to compare the prevalence of cardiovascular disease (CVD) among patients...

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Identifiers

PMID: 26368360
DOI: 10.1111/jth.13142

Genes

VWF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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