Article
Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels.
Blood - 23 Nov 2017
Lavin Michelle, Aguila Sonia, Schneppenheim Sonja, Dalton Niall, Jones Kenneth L, O'Sullivan Jamie M, O'Connell Niamh M, Ryan Kevin, White Barry, Byrne Mary, Rafferty Marie, Doyle Mairead M, Nolan Margaret, Preston Roger J S, Budde Ulrich, James Paula, Di Paola Jorge, O'Donnell James S
Abstract excerpt
Critical clinical questions remain unanswered regarding diagnosis and management of patients with low von Willebrand factor (VWF) levels (30-50 IU/dL). To address these questions, the Low VWF Ireland Cohort (LoVIC) study investigated 126 patients registered with low VWF levels. Despite marginally reduced plasma VWF levels, International Society of Thrombosis and Haemostasis Bleeding Assessment Tool (ISTH BAT)...
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