Article
Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study.
International journal of cardiology - 1 Jan 2015
Hermanns M Iris, Grossmann Vera, Spronk Henri M H, Schulz Andreas, Jünger Claus, Laubert-Reh Dagmar, Mazur Johanna, Gori Tommaso, Zeller Tanja, Pfeiffer Norbert, Beutel Manfred, Blankenberg Stefan, Münzel Thomas, Lackner Karl J, Ten Cate-Hoek Arina J, Ten Cate Hugo, Wild Philipp S
Abstract excerpt
BACKGROUND: Elevated levels of FVIII: c are associated with risk for both venous and arterial thromboembolism. However, no population-based study on the sex-specific distribution and reference ranges of plasma FVIII: c and its cardiovascular determinants is available. METHODS: FVIII: c was analyzed in a randomly selected sample of 2533 males and 2440 females from the Gutenberg Health Study in Germany....
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