Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2012

van Loon J E, Kavousi M, Leebeek F W G, Felix J F, Hofman A, Witteman J C M, de Maat M P M

Abstract excerpt

BACKGROUND: High von Willebrand factor (VWF) levels are associated with an increased risk of coronary heart disease (CHD). However, it remains unclear whether VWF is causally related to the occurrence of CHD or primarily mirrors endothelial dysfunction, which predisposes to atherosclerosis and subsequent CHD. OBJECTIVES: Because VWF is largely determined by genetic factors, we investigated whether VWF antigen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Coronary Disease

Share to VWF gene

Share to Genetic Variation

Share to Netherlands

Share to von Willebrand Factor

Source

Identifiers

PMID: 22568520
DOI: 10.1111/j.1538-7836.2012.04771.x

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.PMID 22568520Read ↗

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study.Semantic proximity Read ↗

Genetic variability of von Willebrand factor and risk of coronary heart disease: the Rotterdam Study.Semantic proximity Read ↗

Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort.Semantic proximity Read ↗

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.Semantic proximity Read ↗

Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.Semantic proximity Read ↗

Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts.Semantic proximity Read ↗

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review.Semantic proximity Read ↗

Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding.Semantic proximity Read ↗

Unraveling the Influence of Common von Willebrand factor variants on von Willebrand Disease Phenotype: An Exploratory Study on the Molecular and Clinical Profile of von Willebrand Disease in Spain Cohort.Semantic proximity Read ↗

Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke.Semantic proximity Read ↗

Whole-exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.