Article
CFTR Folding Consortium: methods available for studies of CFTR folding and correction.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Peters Kathryn W, Okiyoneda Tsukasa, Balch William E, Braakman Ineke, Brodsky Jeffrey L, Guggino William B, Penland Christopher M, Pollard Harvey B, Sorscher Eric J, Skach William R, Thomas Philip J, Lukacs Gergely L, Frizzell Raymond A
Abstract excerpt
The CFTR Folding Consortium (CFC) was formed in 2004 under the auspices of the Cystic Fibrosis Foundation and its drug discovery and development affiliate, CFF Therapeutics. A primary goal of the CFC is the development and distribution of reagents and assay methods designed to better understand the mechanistic basis of mutant CFTR misfolding and to identify targets whose manipulation may correct CFTR folding...
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