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Article

Exaggerated Nighttime Sleep and Defective Sleep Homeostasis in a Drosophila Knock-In Model of Human Epilepsy.

PloS one - 1 Jan 2015

Petruccelli Emily, Lansdon Patrick, Kitamoto Toshihiro

Abstract excerpt

Despite an established link between epilepsy and sleep behavior, it remains unclear how specific epileptogenic mutations affect sleep and subsequently influence seizure susceptibility. Recently, Sun et al. (2012) created a fly knock-in model of human generalized epilepsy with febrile seizures plus (GEFS+), a wide-spectrum disorder characterized by fever-associated seizing in childhood and lifelong affliction....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26361221
DOI: 10.1371/journal.pone.0137758
PMCID: PMC4567262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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