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Article

Derepression of MicroRNA-138 Contributes to Loss of the Human Articular Chondrocyte Phenotype.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Feb 2016

Seidl Christine I, Martinez-Sanchez Aida, Murphy Christopher L

Abstract excerpt

OBJECTIVE: To investigate the function of microRNA-138 (miR-138) in human articular chondrocytes (HACs). METHODS: The expression of miR-138 in intact cartilage and cultured chondrocytes and the effects of miR-138 overexpression on chondrocyte marker genes were investigated. Targets of miR-138 relevant to chondrocytes were identified and verified by overexpression of synthetic miRNA mimics and inhibitors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26359943
DOI: 10.1002/art.39428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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