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Article

MicroRNA Signatures in Cartilage Ageing and Osteoarthritis

17 Apr 2023

Abstract excerpt

Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene expression regulators that act post-transcriptionally to control tissue homeostasis. Microarray analysis was undertaken in osteoarthritic intact, lesioned and young intact cartilage. Principal component analysis showed that young intact cartilage samples were clustered together; osteoarthritic samples had a wider distribution; and...

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PMID: 37189806
DOI: 10.3390/biomedicines11041189

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