Article
Recombination increases human immunodeficiency virus fitness, but not necessarily diversity.
The Journal of general virology - 1 Jun 2008
Vijay N N V, Vasantika, Ajmani Rahul, Perelson Alan S, Dixit Narendra M
Abstract excerpt
Recombination can facilitate the accumulation of mutations and accelerate the emergence of resistance to current antiretroviral therapies for human immunodeficiency virus (HIV) infection. Yet, since recombination can also dissociate favourable combinations of mutations, the benefit of recombination to HIV remains in question. The confounding effects of mutation, multiple infections of cells, random genetic drift...
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