Article
MMBIRFinder: A Tool to Detect Microhomology-Mediated Break-Induced Replication.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Segar Matthew W, Sakofsky Cynthia J, Malkova Anna, Liu Yunlong
Abstract excerpt
The introduction of next-generation sequencing technologies has radically changed the way we view structural genetic events. Microhomology-mediated break-induced replication (MMBIR) is just one of the many mechanisms that can cause genomic destabilization that may lead to cancer. Although the mechanism for MMBIR remains unclear, it has been shown that MMBIR is typically associated with template-switching events....
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