Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Genetic Network Associated With Stress Resistance, Longevity, and Cancer in Humans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jun 2016

Levine Morgan E, Crimmins Eileen M

Abstract excerpt

Human longevity and diseases are likely influenced by multiple interacting genes within a few biologically conserved pathways. Using long-lived smokers as a phenotype (n = 90)-a group whose survival may signify innate resilience-we conducted a genome-wide association study comparing them to smokers at ages 52-69 (n = 730). These results were used to conduct a functional interaction network and pathway analysis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Gene Regulatory Networks
Share to Longevity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Longitudinal Studies

Share to Neoplasms

Share to Smoking

Share to Stress, Physiological

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 26355015
DOI: 10.1093/gerona/glv141
PMCID: PMC4888382

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Genetic Network Associated With Stress Resistance, Longevity, and Cancer in Humans.PMID 26355015Read ↗

Functional diversity in the gene network controlled by the master regulator p53 in humans.Semantic proximity Read ↗

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participantsSemantic proximity Read ↗

Genetics of human longevity: From variants to genes to pathwaysSemantic proximity Read ↗

Biology of healthy aging: Biological hallmarks of stress resistance-related and unrelated to longevity in humansSemantic proximity Read ↗

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.Semantic proximity Read ↗

Panoramic smoking burden and genetic susceptibility in relation to all-cause and cause-specific mortality: a prospective study in UK Biobank.Semantic proximity Read ↗

The genetics of human longevity: an intricacy of genes, environment, culture and microbiome.Semantic proximity Read ↗

Genetic predisposition, modifiable lifestyles, and their joint effects on human lifespan: evidence from multiple cohort studies.Semantic proximity Read ↗

Integrative Analysis of Oxidative Stress and Cellular Senescence Pathways in Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

Identification of polymorphisms in cancer patients that differentially affect survival with age.Semantic proximity Read ↗

Genomics of human health and aging.Semantic proximity Read ↗

Red-wine gene networks associated with exceptional longevity in humansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.