Article
HaloPlex Targeted Resequencing for Mutation Detection in Clinical Formalin-Fixed, Paraffin-Embedded Tumor Samples.
The Journal of molecular diagnostics : JMD - 1 Nov 2015
Moens Lotte N J, Falk-Sörqvist Elin, Ljungström Viktor, Mattsson Johanna, Sundström Magnus, La Fleur Linnéa, Mathot Lucy, Micke Patrick, Nilsson Mats, Botling Johan
Abstract excerpt
In recent years, the advent of massively parallel next-generation sequencing technologies has enabled substantial advances in the study of human diseases. Combined with targeted DNA enrichment methods, high sequence coverage can be obtained for different genes simultaneously at a reduced cost per sample, creating unique opportunities for clinical cancer diagnostics. However, the formalin-fixed, paraffin-embedded...
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