Article
Molecular classification of anaplastic oligodendroglioma using next-generation sequencing: a report of the prospective randomized EORTC Brain Tumor Group 26951 phase III trial.
Neuro-oncology - 1 Mar 2016
Dubbink Hendrikus J, Atmodimedjo Peggy N, Kros Johan M, French Pim J, Sanson Marc, Idbaih Ahmed, Wesseling Pieter, Enting Roelien, Spliet Wim, Tijssen Cees, Dinjens Winand N M, Gorlia Thierry, van den Bent Martin J
Abstract excerpt
BACKGROUND: Histopathological diagnosis of diffuse gliomas is subject to interobserver variation and correlates modestly with major prognostic and predictive molecular abnormalities. We investigated a series of patients with locally diagnosed anaplastic oligodendroglial tumors included in the EORTC phase III trial 26951 on procarbazine/lomustine/vincristine (PCV) chemotherapy to explore the diagnostic,...
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