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Article

Systematic stereoscopic analyses for cloacal development: The origin of anorectal malformations.

Scientific reports - 10 Sept 2015

Matsumaru Daisuke, Murashima Aki, Fukushima Junichi, Senda Syuhei, Matsushita Shoko, Nakagata Naomi, Miyajima Masayasu, Yamada Gen

Abstract excerpt

The division of the embryonic cloaca is the most essential event for the formation of digestive and urinary tracts. The defective development of the cloaca results in anorectal malformations (ARMs; 2-5 per 10,000 live births). However, the developmental and pathogenic mechanisms of ARMs are unclear. In the current study, we visualized the epithelia in the developing cloaca and nephric ducts (NDs). Systemic...

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PMID: 26354024
DOI: 10.1038/srep13943
PMCID: PMC4564729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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