Article
The Skt gene, required for anorectal development, is a candidate for a molecular marker of the cloacal plate.
Pediatric surgery international - 1 Mar 2011
Suda Hiroko, Lee Kwang-Jong, Semba Kei, Kyushima Fumie, Ando Takashi, Araki Masatake, Araki Kimi, Inomata Yukihiro, Yamamura Ken-ichi
Abstract excerpt
BACKGROUND AND AIMS: It has been reported that a dorsal cloacal plate defect is associated with anorectal malformations (ARMs); however, there has been very little information reported about the developmental mechanisms involved with cloacal plate formation. Danforth's short tail (Sd) mutant mice show ARMs. In our previous study, the co-presence of Skt ( Gt ) mutation, in which Skt gene is disrupted by the...
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