Article
Uterine Carcinomas in Tetrabromobisphenol A-exposed Wistar Han Rats Harbor Increased Tp53 Mutations and Mimic High-grade Type I Endometrial Carcinomas in Women.
Toxicologic pathology - 1 Dec 2015
Harvey Janice B, Osborne Tanasa S, Hong Hue-Hua L, Bhusari Sachin, Ton Tai-Vu, Pandiri Arun R, Masinde Tiwanda, Dunnick June, Peddada Shyamal, Elmore Susan, Hoenerhoff Mark J
Abstract excerpt
Endometrial carcinoma is the most common gynecologic malignancy is the United States and accounts for 6% of all cancers in women. The disease is classified as type I or type II based on clinicopathologic and molecular features. It is a multifactorial disease with a number of risk factors, including environmental exposures. How environmental exposures, such as flame retardants, may affect the incidence of...
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