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Article

A Primer on the Role of TP53 Mutation and Targeted Therapy in Endometrial Cancer.

Frontiers in bioscience (Landmark edition) - 20 Jan 2025

Zhang Bohao, Zhang Haozhe, Qin Yanru

Abstract excerpt

Endometrial Cancer (EC) is one of the most common gynecological malignancies, ranking first in developed countries and regions. The occurrence and development of EC is closely associated with genetic mutations. TP53 mutation, in particular, can lead to the dysfunction of numerous regulatory factors and alteration of the tumor microenvironment (TME). The changes in the TME subsequently promote the development of...

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Identifiers

PMID: 39862074
DOI: 10.31083/FBL25447

Genes

TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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