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Article

Utility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissue.

International journal of molecular medicine - 1 Nov 2015

Fassunke Jana, Haller Florian, Hebele Simone, Moskalev Evgeny A, Penzel Roland, Pfarr Nicole, Merkelbach-Bruse Sabine, Endris Volker

Abstract excerpt

In the growing field of personalised medicine, the analysis of numerous potential targets is becoming a challenge in terms of work load, tissue availability, as well as costs. The molecular analysis of non-small cell lung cancer (NSCLC) has shifted from the analysis of the epidermal growth factor receptor (EGFR) mutation status to the analysis of different gene regions, including resistance mutations or...

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Identifiers

PMID: 26352389
DOI: 10.3892/ijmm.2015.2339
PMCID: PMC4601747

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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