Article
[EGFR molecular characterization in non-small cell bronchic cancer: comparative prospective study by NGS and Idylla platform technologies].
Annales de pathologie - 1 Sept 2020
Chevalier Louise-Marie, Billaud Amandine, Passot Christophe, Renoult Adélaïde, Bigot Frédéric, Verrièle Véronique, Morel Alain
Abstract excerpt
INTRODUCTION: Detection of genetic alterations in the EGFR tyrosine kinase domain is a major concern in the management of non-small cell lung cancer because it conditions access to tyrosine kinase inhibitors. In practice, it is possible to characterize only well-documented mutations or to sequence all relevant EGFR exons and also other targets of theranostic interest. This prospective study compares the targeted...
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