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Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

4 Mar 2011

Abstract excerpt

To integrate available clinical and molecular information for cytogenetically normal acute myeloid leukemia (CN-AML) patients into one risk score, 275 CN-AML patients from multicenter treatment trials AML SHG Hannover 0199 and 0295 and 131 patients from HOVON/SAKK protocols as external controls were evaluated for mutations/polymorphisms in NPM1, FLT3, CEBPA, MLL, NRAS, IDH1/2, and WT1. Transcript levels were...

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PMID: 21372155
DOI: 10.1182/blood-2010-08-303479

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