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Article

A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development.

The Biochemical journal - 1 Sept 2015

Mariappa Daniel, Selvan Nithya, Borodkin Vladimir, Alonso Jana, Ferenbach Andrew T, Shepherd Claire, Navratilova Iva Hopkins, vanAalten Daan M F

Abstract excerpt

O-GlcNAcylation is a reversible type of serine/threonine glycosylation on nucleocytoplasmic proteins in metazoa. Various genetic approaches in several animal models have revealed that O-GlcNAcylation is essential for embryogenesis. However, the dynamic changes in global O-GlcNAcylation and the underlying mechanistic biology linking them to embryonic development is not understood. One of the limiting factors...

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Identifiers

PMID: 26348912
DOI: 10.1042/BJ20150610
PMCID: PMC4941924

Genes

OGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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