Article
Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.
Molecular and cellular biochemistry - 1 Dec 2015
Naz Farha, Islam Asimul, Ahmad Faizan, Hassan Md Imtaiyaz
Abstract excerpt
MAP/Microtubule affinity-regulating kinase 4 (MARK4), a Ser/Thr protein kinases, is related to the Par-1 (partitioning-defective) gene products, and is the human ortholog of Par-1. MARK4 shows its role in the cell polarity at the time of embryonic development. It is mostly located at the basal region of cells, providing apico-basal polarity. Here, we made two variants of human Par-1d (MARK4), kinase domain...
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