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Article

Genomic and transcriptomic profiling of peripheral T cell lymphoma reveals distinct molecular and microenvironment subtypes.

Cell reports. Medicine - 20 Feb 2024

Huang Yao-Hui, Qiu Yu-Ran, Zhang Qun-Ling, Cai Ming-Ci, Yu Hao, Zhang Jian-Ming, Jiang Lu, Ji Meng-Meng, Xu Peng-Peng, Wang Li, Cheng Shu, Zhao Wei-Li

Abstract excerpt

Peripheral T cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin's lymphomas varying in clinical, phenotypic, and genetic features. The molecular pathogenesis and the role of the tumor microenvironment in PTCL are poorly understood, with limited biomarkers available for genetic subtyping and targeted therapies. Through an integrated genomic and transcriptomic study of 221 PTCL patients, we delineate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38350451
DOI: 10.1016/j.xcrm.2024.101416
PMCID: PMC10897627

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