Article
Mutation-derived, genomic instability-associated lncRNAs are prognostic markers in gliomas.
PeerJ - 1 Jan 2023
Li Shenglun, Chen Yujia, Guo Yuduo, Xu Jiacheng, Wang Xiang, Ning Weihai, Ma Lixin, Qu Yanming, Zhang Mingshan, Zhang Hongwei
Abstract excerpt
Background: Gliomas are the most commonly-detected malignant tumors of the brain. They contain abundant long non-coding RNAs (lncRNAs), which are valuable cancer biomarkers. LncRNAs may be involved in genomic instability; however, their specific role and mechanism in gliomas remains unclear. LncRNAs that are related to genomic instability have not been reported in gliomas. Methods: The transcriptome data from The...
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