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Article

Identification and validation of a novel eight mutant-derived long non-coding RNAs signature as a prognostic biomarker for genome instability in low-grade glioma.

Aging - 3 Jun 2021

Maimaiti Aierpati, Wang Xixian, Pei Yinan, Nuermaimaiti Nuerbiye, Tuersunniyazi Abudireheman, Abula Yaeraili, Feng Zhaohai, Jiang Lei, Shi Xin, Kasimu Maimaitijiang

Abstract excerpt

Long non-coding RNAs (lncRNAs) comprise an integral part of the eukaryotic transcriptome. Alongside proteins, lncRNAs modulate lncRNA-based gene signatures of unstable transcripts, play a crucial role as antisense lncRNAs to control intracellular homeostasis and are implicated in tumorigenesis. However, the role of genomic instability-associated lncRNAs in low-grade gliomas (LGG) has not been fully explored. In...

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Identifiers

PMID: 34081618
DOI: 10.18632/aging.203079
PMCID: PMC8221298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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