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Article

Chromosomal catastrophe is a frequent event in clinically insignificant prostate cancer.

Oncotarget - 6 Oct 2015

Kovtun Irina V, Murphy Stephen J, Johnson Sarah H, Cheville John C, Vasmatzis George

Abstract excerpt

Massive genomic rearrangements, a result of single catastrophic event termed chromothrispsis or chromosomal catastrophe, have been identified in a variety of human cancers. In a few cancer types, chromothripsis was found to be associated with poor prognosis. We performed mate-pair sequencing and analysis of structural rearrangements in 132 prostate cancer cases which included clinically insignificant Gleason...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26337081
DOI: 10.18632/oncotarget.4900
PMCID: PMC4745713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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