Article
MCP1 2518 A/G polymorphism affects progression of childhood focal segmental glomerulosclerosis.
Renal failure - 1 Jan 2015
Besbas Nesrin, Kalyoncu Mukaddes, Cil Onur, Ozgul Riza Koksal, Bakkaloglu Aysin, Ozaltin Fatih
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1) is a highly specific chemokine for monocytes and plays roles in pathogenesis of various renal diseases. The aim of this study is to investigate the effect of MCP1 2518 A/G polymorphism on the incidence and clinical course of focal segmental glomerulosclerosis (FSGS) in children. MCP1 2518 A/G genotype was identified by PCR-RFLP in 60 biopsy-proven FSGS patients, 76...
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