Article
Monocyte chemoattractant protein-1 A-2518G gene polymorphism and renal survival of Japanese patients with immunoglobulin A nephropathy.
Clinical and experimental nephrology - 1 Dec 2005
Mori Honami, Kaneko Yoshikatsu, Narita Ichiei, Goto Shin, Saito Noriko, Kondo Daisuke, Sato Fuminori, Ajiro Junya, Saga Daisuke, Ogawa Asa, Sakatsume Minoru, Ueno Mitsuhiro, Tabei Kaoru, Gejyo Fumitake
Abstract excerpt
BACKGROUND: Monocyte chemoattractant protein (MCP)-1 is closely related to the pathogenesis of the progression of various chronic renal diseases, including IgA nephropathy (IgAN), through its chemoattractant effect on macrophages. However, the correlation of MCP-1 gene polymorphism with the long-term prognosis of Japanese patients with IgAN has not been clearly determined yet. METHODS: We investigated 277...
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