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Article

A cannabinoid receptor 1 polymorphism is protective against major depressive disorder in methadone-maintained outpatients.

The American journal on addictions - 1 Oct 2015

Icick Romain, Peoc'h Katell, Karsinti Emily, Ksouda Kamilla, Hajj Aline, Bloch Vanessa, Prince Nathalie, Mouly Stéphane, Bellivier Frank, Lépine Jean-Pierre, Laplanche Jean-Louis, Vorspan Florence

Abstract excerpt

BACKGROUND AND OBJECTIVES: The burden of opiate dependence not only relies on somatic complications such as infectious diseases or acute intoxication but also on frequent psychiatric events such as major depressive disorder (MDD) and suicidal behavior (SB). Given the preclinical and clinical evidence regarding the associations between cannabinoid systems and both opiate dependence and psychiatric disorders, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Cannabinoid, CB1

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Source

Identifiers

PMID: 26331953
DOI: 10.1111/ajad.12273

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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