Article
(AAT)n repeat in the cannabinoid receptor gene, CNR1: association with schizophrenia in a Spanish population.
European archives of psychiatry and clinical neuroscience - 1 Oct 2006
Martínez-Gras Isabel, Hoenicka Janet, Ponce Guillermo, Rodríguez-Jiménez Roberto, Jiménez-Arriero Miguel Angel, Pérez-Hernandez Elena, Ampuero Israel, Ramos-Atance Jose Antonio, Palomo Tomas, Rubio Gabriel
Abstract excerpt
The cannabinoid receptor 1 gene (CNR1) has been associated with addictive disorders and schizophrenia in different studies. We have compared the frequencies of the alleles for the 3'-UTR CNR1 microsatellite in a sample of 113 Spanish schizophrenic patients, including 68 with comorbid substance abuse, and 111 healthy controls. We report that the frequency of the allele 4 of this microsatellite is significantly...
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