Article
Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression.
Pharmacological research - 1 May 2010
Monteleone Palmiero, Bifulco Maurizio, Maina Giuseppe, Tortorella Alfonso, Gazzerro Patrizia, Proto Maria Chiara, Di Filippo Carmela, Monteleone Francesco, Canestrelli Benedetta, Buonerba Giovanna, Bogetto Filippo, Maj Mario
Abstract excerpt
Experimental data suggest that the endogenous cannabinoid system is involved in mood regulation, but no study has been performed so far to investigate the role of endocannabinoid genes in the susceptibility to major depression (MD) and/or bipolar disorder (BD). We assessed the CB1 receptor gene (...
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