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Article

Investigation of CNR1 and FAAH endocannabinoid gene polymorphisms in bipolar disorder and major depression.

Pharmacological research - 1 May 2010

Monteleone Palmiero, Bifulco Maurizio, Maina Giuseppe, Tortorella Alfonso, Gazzerro Patrizia, Proto Maria Chiara, Di Filippo Carmela, Monteleone Francesco, Canestrelli Benedetta, Buonerba Giovanna, Bogetto Filippo, Maj Mario

Abstract excerpt

Experimental data suggest that the endogenous cannabinoid system is involved in mood regulation, but no study has been performed so far to investigate the role of endocannabinoid genes in the susceptibility to major depression (MD) and/or bipolar disorder (BD). We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420...

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Source

Identifiers

PMID: 20080186
DOI: 10.1016/j.phrs.2010.01.002

Genes

CNR1
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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