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Article

Pharmacokinetics of venlafaxine enantiomers and their metabolites in psoriasis patients.

Journal of clinical pharmacology - 1 May 2016

Godoy Ana Leonor Pardo Campos, Rocha Adriana, da Silva Souza Cacilda, Lanchote Vera Lucia

Abstract excerpt

Psoriasis is a chronic inflammatory disease associated with several comorbidities, including depression. Previous studies have shown that inflammatory diseases downregulate the expression and suppress activity of CYP isoforms. Venlafaxine (VLX) is an antidepressant metabolized mainly by CYP2D6 to O-desmethylvenlafaxine (ODV), CYP3A to N-desmethylvenlafaxine (NDV), and CYP2D6 and CYP3A to...

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Identifiers

PMID: 26331791
DOI: 10.1002/jcph.630

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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