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Article

Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies.

Oncotarget - 22 Sept 2015

Telonis Aristeidis G, Loher Phillipe, Honda Shozo, Jing Yi, Palazzo Juan, Kirino Yohei, Rigoutsos Isidore

Abstract excerpt

We analyzed transcriptomic data from 452 healthy men and women representing five different human populations and two races, and, 311 breast cancer samples from The Cancer Genome Atlas. Our studies revealed numerous constitutive, distinct fragments with overlapping sequences and quantized lengths that persist across dozens of individuals and arise from the genomic loci of all nuclear and mitochondrial human...

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Identifiers

PMID: 26325506
DOI: 10.18632/oncotarget.4695
PMCID: PMC4694795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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