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Article

Population-dependent contribution of the major histocompatibility complex region to schizophrenia susceptibility.

Schizophrenia research - 1 Oct 2015

Yamada Kazuo, Hattori Eiji, Iwayama Yoshimi, Toyota Tomoko, Iwata Yasuhide, Suzuki Katsuaki, Kikuchi Mitsuru, Hashimoto Tasuku, Kanahara Nobuhisa, Mori Norio, Yoshikawa Takeo

Abstract excerpt

There is consistent data from European cohorts suggesting a genetic contribution from the major histocompatibility complex (MHC) to the pathogenesis of schizophrenia. However, the genomic complexity and ethnicity-specific diversity found in the MHC cause difficulties in identifying causal variant...

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Source

Identifiers

PMID: 26324334
DOI: 10.1016/j.schres.2015.08.018

Genes

MSH5
SAPCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26324334-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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